【発明の名称】ハプテン誘導体、その製法、ハプテン/蛋白質―接合体、その製法、抗体の製法及びイムノアッセイの標識酵素

Title:

【発明の名称】ハプテン誘導体、その製法、ハプテン/蛋白質―接合体、その製法、抗体の製法及びイムノアッセイの標識酵素

Document Type and Number:

Japanese Patent JPH0633315

Kind Code:

B2

Abstract:

Hapten derivatives of the general formula (I) …… in which Hap is the radical formed by elimination of an oxo group from a hapten with keto or aldehyde groups, and R<1> and R<2> are identical or different and are a lower alkyl group with 1 to 7, in particular 1 to 3, carbon atoms, and one radical R<1> or R<2> can also be a hydrogen atom, as well as the hapten-protein conjugates formed from these hapten derivatives (I), of the formula (III) …… in which E-NH- is the radical of a protein bonded via an epsilon -amino group of a lysine residue, are described. …The hapten-protein conjugates of the formula (III) are very suitable for use for the immunisation of organisms suitable for antibody production and as labelling enzyme in immunoassays.

Inventors:

ERASUMUSU FUUBAA
KURISUCHAN KURAIN
GUNTAA PATSUPERUTO
KURAUSU HARAAMAIYAA

Application Number:

JP1331589A

Publication Date:

May 02, 1994

Filing Date:

January 24, 1989

Export Citation:

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Assignee:

BOEHRINGER MANNHEIM GMBH

International Classes:

G01N33/53; A61K39/385; C07H15/26; C07J1/00; C07J41/00; C07J43/00; C07K14/00; C12P21/08; G01N33/531; G01N33/532; G01N33/535; G01N33/543; G01N33/74; G01N33/94; (IPC1-7): C07J1/00; A61K39/385; C07K15/12; C12P21/08; G01N33/53; G01N33/531; G01N33/535

Attorney, Agent or Firm:

Toshio Yano (1 outside)

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