Title:
【発明の名称】新規化合物WF00144
Document Type and Number:
Japanese Patent JP2002510335
Kind Code:
A
Abstract:
The present invention provides a new bioactive compound, WF00144 substance or its salt which has an inhibitory activity against gluconeogenesis, and a process for production of the same, which comprises culturing a WF00144 substance-producing strain belonging to the genus Phoma in a nutrient medium and recovering the WF00144 substance. Also provided are a pharmaceutical composition containing the WF00144 substance or pharmaceutically acceptable salt thereof, a use of the WF00144 substance as a medicament and use of the WF00144 substance for the manufacture of a medicament for therapeutic treatment or prevention of diabetes in human or animal.
Inventors:
Yoshihiro Otsu
Miho Tanaka
Toshihiro Shibata
Norito Sakamoto
Tsuruumi Yasuhisa
Takase Shigehiro
Hino Yoshihiro
Miho Tanaka
Toshihiro Shibata
Norito Sakamoto
Tsuruumi Yasuhisa
Takase Shigehiro
Hino Yoshihiro
Application Number:
JP54687699A
Publication Date:
April 02, 2002
Filing Date:
May 21, 1999
Export Citation:
Assignee:
Fujisawa Pharmaceutical Co., Ltd.
International Classes:
A61K35/74; A61P3/10; A61P43/00; C07G99/00; C12N1/14; C12P1/02; C12R1/645; (IPC1-7): C07G17/00; C12N1/14; C12P1/02
Attorney, Agent or Firm:
Eiji Tabushi