【発明の名称】17β-N-モノ置換カルバモイル-4-アザ-5α-アンドロスタン-3-オンの酸化同族体

Title:

【発明の名称】17β-N-モノ置換カルバモイル-4-アザ-5α-アンドロスタン-3-オンの酸化同族体

Document Type and Number:

Japanese Patent JP2592870

Kind Code:

B2

Abstract:

The compounds of formula (I) wherein R is selected from hydrogen, methyl or ethyl, and R<1> is C1-12 straight or branched chain alkyl wherein one of the hydrogens is substituted by hydroxy, carboxylic acid or C1-4 alkyl ester, and A is -CH2-CH2 or -CH=CH-, and pharmaceutical formulations of the above compounds are active as testosterone 5 alpha -reductase inhibitors and thus are useful for treatment of acne, seborrhea, female hirsutism or benign prostatic hypertrophy.

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Inventors:

JOSEFUIINU AARU KAARIN
GYARII ETSUCHI RASUMUSON
DABURYU JEE EE UANDENHEEUERU

Application Number:

JP29221387A

Publication Date:

March 19, 1997

Filing Date:

November 20, 1987

Export Citation:

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Assignee:

MERCK & CO INC

International Classes:

A61K31/435; A61P5/00; A61P13/02; A61K31/58; A61P15/00; A61P17/00; C07J73/00; (IPC1-7): C07J73/00; A61K31/58

Attorney, Agent or Firm:

Masao Okabe (2 outside)

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