Title:
【発明の名称】チオール誘導化ヌクレオシドおよびオリゴヌクレオシド
Document Type and Number:
Japanese Patent JP3256236
Kind Code:
B2
Abstract:
Nucleosides and linked nucleosides functionalized to include alkylthiol chemical functionality at ribofuranosyl positions, nucleosidic base positions, or on internucleoside linkages. In certain embodiments, the compounds of the invention further include steroids, reporter molecules, reporter enzymes, lipophilic molecules, peptides or proteins attached to the nucleosides through the alkylthio group.
Inventors:
Cook, Philip Dunn
Manoharan, Musier
Manoharan, Musier
Application Number:
JP50832295A
Publication Date:
February 12, 2002
Filing Date:
August 31, 1994
Export Citation:
Assignee:
Isis PharmaceuticalsInc
International Classes:
A01N43/04; C07C323/02; C07H19/04; C07H19/06; C07H19/067; C12N15/09; C07H19/10; C07H19/16; C07H19/167; C07H19/20; C07H21/00; C07H21/02; C07H21/04; C07H23/00; C07J1/00; C07J31/00; C07J43/00; C07J51/00; C07K9/00; C12N9/00; C12N9/02; C12N15/113; C12Q1/68; A61K38/00; A61K48/00; (IPC1-7): C07H19/067; C07H19/167; C07H21/02; C07H21/04; C07J31/00; C12Q1/68
Domestic Patent References:
| JP6256381A | ||||
| JP5504552A |
Attorney, Agent or Firm:
Kazuo Shamoto (5 outside)