Title:
【発明の名称】核酸トランスフェクション因子として使用するためのステロイドホルモンを含むDNA相互作用基の抱合体
Document Type and Number:
Japanese Patent JP2002523422
Kind Code:
A
Abstract:
The present invention relates to novel compounds comprising a steroid hormone linked to a DNA-interacting molecule that target nucleic acids to the cell nucleus. Further, the invention relates to a method for introducing nucleic acids into the nucleus of cells with the help of such compounds. Pharmaceutical preparations containing such compounds and the use of such compounds for gene therapy are also provided.
Inventors:
Frey, Felix
Rascone, Sandro
Frey, Bridget
Veli, Hans-Willie
Rascone, Sandro
Frey, Bridget
Veli, Hans-Willie
Application Number:
JP2000566290A
Publication Date:
July 30, 2002
Filing Date:
August 19, 1999
Export Citation:
Assignee:
Frey, Felix
Rascone, Sandro
Rascone, Sandro
International Classes:
C12N15/09; A61K31/575; A61K31/58; A61K35/12; A61K38/00; A61K48/00; A61P5/24; A61P5/26; A61P5/30; A61P5/38; A61P5/40; A61P5/44; A61P43/00; C07J17/00; C07J41/00; C07J43/00; C12N5/10; C12N15/87; C12Q1/02; C12Q1/68; (IPC1-7): C07J17/00; A61K31/575; A61K31/58; A61K35/12; A61K38/00; A61K48/00; A61P5/24; A61P5/26; A61P5/30; A61P5/38; A61P5/40; A61P5/44; A61P43/00; C07J41/00; C07J43/00; C12N5/10; C12N15/09; C12Q1/02; C12Q1/68
Foreign References:
| WO1996018372A2 | 1996-06-20 | |||
| WO1996003875A1 | 1996-02-15 |
Attorney, Agent or Firm:
Yosuke Goto (1 person outside)