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Title:
【発明の名称】蛋白質キナーゼ活性の調節剤としての幾何学的に制限された2-インドリノン誘導体
Document Type and Number:
Japanese Patent JP2002523455
Kind Code:
A
Abstract:
The present invention relates to novel geometrically restricted 2-indolinones and physiologically acceptable salts thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Inventors:
Tan, pen, cho
Miller, Todd Anthony
Sun lee
Trang, Engoku Mai
Nematara, asado
Nguyen, Ann Tee
Application Number:
JP2000567201A
Publication Date:
July 30, 2002
Filing Date:
August 30, 1999
Export Citation:
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Assignee:
SUGEN,INC.
International Classes:
A61K31/404; A61K31/34; A61K31/35; A61K31/36; A61K31/38; A61K31/385; A61K31/39; A61K31/40; A61K31/403; A61K31/405; A61K31/41; A61K31/415; A61K31/42; A61K31/425; A61K31/435; A61K31/44; A61K31/445; A61K31/495; A61K31/50; A61K31/505; A61K31/517; A61K31/519; A61K31/53; A61K31/535; A61K31/54; A61P3/10; A61P7/00; A61P9/08; A61P17/06; A61P19/02; A61P29/00; A61P35/00; A61P37/02; A61P43/00; C07D209/12; C07D209/34; C07D231/54; C07D235/02; C07D237/26; C07D239/70; C07D241/36; C07D249/16; C07D251/16; C07D251/72; C07D253/065; C07D253/08; C07D257/04; C07D257/08; C07D257/10; C07D261/08; C07D261/20; C07D263/32; C07D263/52; C07D265/12; C07D265/16; C07D265/34; C07D265/36; C07D271/04; C07D271/06; C07D271/08; C07D271/10; C07D271/12; C07D273/04; C07D275/02; C07D275/04; C07D279/06; C07D279/08; C07D279/12; C07D279/14; C07D279/16; C07D285/06; C07D285/08; C07D285/10; C07D285/12; C07D285/14; C07D285/18; C07D285/20; C07D285/22; C07D285/34; C07D291/02; C07D291/08; C07D307/36; C07D307/38; C07D307/40; C07D307/52; C07D307/77; C07D311/02; C07D311/94; C07D317/04; C07D317/06; C07D317/14; C07D317/44; C07D317/46; C07D319/06; C07D319/08; C07D319/12; C07D319/14; C07D319/16; C07D323/02; C07D323/04; C07D327/04; C07D327/06; C07D327/10; C07D333/06; C07D333/50; C07D401/02; C07D401/10; C07D403/04; C07D471/02; C07D487/02; (IPC1-7): C07D209/34; A61K31/404; A61P3/10; A61P7/00; A61P9/08; A61P17/06; A61P19/02; A61P29/00; A61P35/00; A61P37/02; A61P43/00
Attorney, Agent or Firm:
Reiko Tanaka (1 person outside)