Title:
【発明の名称】10位置に置換基を持つ新ステロイドの製造用中間体
Document Type and Number:
Japanese Patent JP2687209
Kind Code:
B2
Abstract:
A novel steroid of the formula I wherein X is methylene and R is an optionally substituted carbocyclic aryl or heterocyclic aryl or optionally substituted vinyl or ethynyl or X is a simple bond or -S- and R is optionally substituted carbocyclic aryl or heterocyclic aryl, R2 is methyl or ethyl, R3 is selected from the group consisting of optionally substituted alkyl of 1 to 8 carbon atoms and optionally substituted alkenyl and alkynyl of 2 to 8 carbon atoms, R4 is selected from the group consisting of hydrogen and acyl, is selected from the group consisting of R6 is selected from the group consisting of hydrogen and methyl, the wavy line indicates alpha or beta - and the dotted line in 1(2) indicates the optional presence of a second carbon-carbon bond and novel process and intermediates therefore having anti-glucocorticoid activity.
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Inventors:
Jean-Georges Tooch
Germain Costruth
Vespelt Trelli
Daniel Huilibert
Germain Costruth
Vespelt Trelli
Daniel Huilibert
Application Number:
JP33686594A
Publication Date:
December 08, 1997
Filing Date:
December 27, 1994
Export Citation:
Assignee:
Roussel-Yukraf
International Classes:
A61K31/57; A61K31/575; A61K31/58; A61P3/04; A61P3/08; A61P3/10; A61P5/38; A61K31/565; A61P9/10; A61P9/12; A61P25/20; A61P27/02; A61P27/06; A61P29/00; A61P37/04; A61P43/00; C07J1/00; C07J3/00; C07J5/00; C07J7/00; C07J9/00; C07J17/00; C07J21/00; C07J31/00; C07J33/00; C07J41/00; C07J43/00; C07J51/00; H02J3/18; (IPC1-7): C07J1/00; C07J17/00; C07J31/00; C07J33/00; C07J43/00
Attorney, Agent or Firm:
Motohiro Kurauchi (1 outside)