Title:
【発明の名称】共通プロフィールを用いて薬物活性を特性決定する方法
Document Type and Number:
Japanese Patent JP2003520567
Kind Code:
A
Abstract:
The present invention provides methods for enhanced detection of biological response profiles. In particular, the methods of this invention allow for the detection of biological response patterns, such as gene expression patterns, in response to different drug treatments. The methods of the invention also allow the determination of a "consensus profile" which describes a particular class or type of biological response. In certain embodiments the consensus profile may describe the biological response of a particular group or class of drugs. In other embodiments, the consensus profile may describe an "ideal" biological response such as one associated with a desired therapeutic effect. The methods of the present invention also allow for the comparison of different biological responses. Thus, the methods of the invention may be used, e.g., to identify and/or study new drugs.
Inventors:
Friendo, Stefan, H.
Stowton, Roland
Hae, Yu Dong
Stowton, Roland
Hae, Yu Dong
Application Number:
JP2000591224A
Publication Date:
July 08, 2003
Filing Date:
December 21, 1999
Export Citation:
Assignee:
Rosetta Inpharmatics,Inc.
International Classes:
C12N15/09; G16B40/30; C12Q1/02; C12Q1/68; G01N33/15; G01N33/566; G06F17/30; G16B25/10; (IPC1-7): C12N15/09; C12Q1/02; C12Q1/68; G01N33/15; G01N33/566; G06F17/30
Attorney, Agent or Firm:
Yusuke Hiraki (1 person outside)