Title:
【発明の名称】システイン・プロテアーゼあるいはその断片を含む連鎖球菌を識別するための方法および組成物
Document Type and Number:
Japanese Patent JPH10505752
Kind Code:
A
Abstract:
Methods and compositions are provided for identifying a group A Streptococcus in any of a variety of physiological samples, such as blood, saliva, throat swabs, cerebrospinal fluid, brocheolar lavage material, and biopsy material. The positions used include an extracellular cysteine protease or a fragment thereof, obtainable from S. pyogenes and containing at least one conserved epitope, or nucleic acid encoding the cysteine protease or fragment thereof. The compositions also find use in eliciting a protective immune response against a group A streptococcus infection.
Inventors:
Miyuther, James, A.
Kapoor, Vivek
Kapoor, Vivek
Application Number:
JP51036496A
Publication Date:
June 09, 1998
Filing Date:
September 13, 1995
Export Citation:
Assignee:
Baylor College of Medicine
International Classes:
A61K39/00; A61K39/09; A61P7/00; A61P11/04; A61P13/12; A61P17/00; A61P29/00; A61P31/04; C07K7/06; C07K7/08; C07K14/315; C12N1/15; C12N1/19; C12N1/21; C12N15/09; C12N5/10; C12N9/52; C12N15/02; C12N15/57; C12P21/08; C12Q1/14; C12Q1/37; C12Q1/68; G01N33/53; G01N33/566; G01N33/569; G01N33/573; G01N33/577; C12R1/46; (IPC1-7): C12Q1/14; G01N33/577; G01N33/573; G01N33/569; G01N33/566; G01N33/53; C12Q1/68; C12Q1/37; C12P21/08; C12N15/09; C12N15/02; C12N5/10; C07K14/315; A61K39/09
Attorney, Agent or Firm:
Morio Sada