Title:
【発明の名称】GDF-5を含む細胞外マトリックスで軟骨形成を誘発又は増強する方法。
Document Type and Number:
Japanese Patent JP2002527402
Kind Code:
A
Abstract:
A method and composition are provided for inducing or enhancing chondrogenesis in vivo or in vitro. The method is performed by exposing the cells in vitro or in vivo to an extracellular matrix comprising of type I collagen, type II collagen or a mixture of type I collagen or type II collagen and hyaluronate and further containing GDF-5.
Inventors:
Haydaran, Mohammad, A.
Spiro, Robert, Sea.
Robin, Daverman
Ryu, Linshu
Spiro, Robert, Sea.
Robin, Daverman
Ryu, Linshu
Application Number:
JP2000575523A
Publication Date:
August 27, 2002
Filing Date:
October 14, 1999
Export Citation:
Assignee:
OQuest Incorporated
International Classes:
A61K31/728; A61K38/17; A61K38/18; A61K38/27; A61K38/39; A61P19/00; C12N5/00; C12N5/077; (IPC1-7): A61K38/17; A61K31/728; A61K38/27; A61P19/00; C12N5/06
Domestic Patent References:
| JPH07116240A | 1995-05-09 |
Foreign References:
| WO1996025961A1 | 1996-08-29 | |||
| WO1998031345A1 | 1998-07-23 |
Attorney, Agent or Firm:
Yuichi Yamada (1 person outside)