Title:
【発明の名称】統計的信頼区間の決定を含む多成分分析方法
Document Type and Number:
Japanese Patent JP3287361
Kind Code:
B2
Abstract:
A signal processing method in a processor is provided for performing a multicomponent analysis of a signal resulting from a spectral response of a mixture comprising a plurality of spectrally resolvable molecular species. The method provides both a determination of a concentration estimate and a statistical confidence interval for each species. In the method, a data vector d is received from a multichannel detector, data vector d having a length nc, nc being the number of detector channels being monitored. A calibration matrix K having nc rows and np columns is provided wherein nc is larger than np, np being the number of spectrally resolvable molecular species. Next, a concentration estimate vector c having length np is determined. Finally, a confidence interval CIi for each of the elements of the concentration estimate vector is determined according to the expressionCIi=ci+/-(varcovar(cii))+E,fra 1/2+EE Q(cl,nf)where Q is the critical value of a statistical distribution for a given level of confidence, cl, and a given number of degrees of freedom nf where nf=nc-np. The invention further includes a program storage device embodying the method; a DNA sequencing process employing the method; and, an apparatus for carrying out the method.
Inventors:
Sharaf, Muhammad A.
Application Number:
JP50059298A
Publication Date:
June 04, 2002
Filing Date:
May 15, 1997
Export Citation:
Assignee:
PI Corporation (NW)
International Classes:
C12Q1/68; G01N21/27; C12N15/09; G01N21/64; G01N27/416; G01N27/42; G01N27/447; G01N30/74; G01N30/86; G01N33/50; G06F17/00; (IPC1-7): G01N21/64; G01N21/27
Domestic Patent References:
| JP5281138A | ||||
| JP4265839A | ||||
| JP60205336A | ||||
| JP1242941A |
Attorney, Agent or Firm:
Shusaku Yamamoto
Previous Patent: 高効率マルチエバポレータサイクル（ＨＩＧＨ ＥＦＦＩＣＩＥＮＣＹ Ｍ...
Next Patent: SPHERE PROCESSING DEVICE AND METHOD
Next Patent: SPHERE PROCESSING DEVICE AND METHOD