Title:
【発明の名称】金属イオンと錯体を形成するためのポリアザマクロサイクリック化合物
Document Type and Number:
Japanese Patent JP3411919
Kind Code:
B2
Abstract:
A nuclear magnetic resonance contrast composition which comprises a tetraazamacrocyclic compound - paramagnetic lanthanide complex having the formula: where x is 2, 3 or a combination of p 2(s) and q 3(s) where p + q = 4; R is (CH2)zP(=O)OR<1>OR<2>; R<1> is H or CH3; R<2> is CnH1+2n; z is 1 to 3; r is 2 or 3; M is a paramagnetic lanthanide; and n is 4 to 6. The nuclear magnetic resonance contrast compositions are particularly suitable for liver imaging in a subject.
More Like This:
Inventors:
Shelley, Alan Dean
Keefer, Garry E
Keefer, Garry E
Application Number:
JP50529794A
Publication Date:
June 03, 2003
Filing Date:
June 28, 1993
Export Citation:
Assignee:
Board Of Regents, The University Of Texas System
The Dow Chemical Company
The Dow Chemical Company
International Classes:
A61K49/04; A61K49/06; A61K51/00; A61K51/04; A61K49/00; C07D255/02; C07D257/02; C07D259/00; C07F9/6515; C07F9/6524; C08G59/70; C07F; (IPC1-7): C07F9/6524; A61K49/00; A61K49/04; A61K51/00
Domestic Patent References:
| JP5500969A | ||||
| JP6502645A |
Attorney, Agent or Firm:
Nao Okuyama (2 outside)