Title:
【発明の名称】大動脈特異的および横紋筋特異的な筋肉細胞におけるアイソフォームをコードする単一遺伝子、およびその使用
Document Type and Number:
Japanese Patent JP2001511016
Kind Code:
A
Abstract:
Aortic-preferentially-expressed gene-1 (APEG-1) and striated muscle preferentially expressed (SPEG) polypeptide, DNA sequences encoding and controlling the transcription of the APEG-1/SPEG encoding gene, methods of diagnosing vascular injury, methods of conferring smooth muscle-cell specific expression, and methods of inhibiting vascular smooth muscle cell proliferation by increasing the level of APEG-1 at the site of vascular injury.
Inventors:
Ream-En
Hessie Chan-Min
Hessie Chan-Min
Application Number:
JP53496598A
Publication Date:
August 07, 2001
Filing Date:
February 06, 1998
Export Citation:
Assignee:
President and Fellows of Harvard College
International Classes:
C07K14/47; C12N15/09; C12N5/10; C12N15/12; A61K38/00; A61K48/00; (IPC1-7): C12N15/09; C07K14/47; C12N5/10
Attorney, Agent or Firm:
Shimizu Hatsushi (1 person outside)