Title:
【発明の名称】新規な5HT1a受容体を介するT細胞増殖の調節
Document Type and Number:
Japanese Patent JPH06503816
Kind Code:
A
Abstract:
A method of regulating proliferation of activated T cells exhibiting a 5HT1a receptor by introducing a sufficient amount of agonists or antagonists to either increase or decrease T cell proliferation. The basis for regulating cell proliferation may be (1) via the 5HT receptor, (2) via serotonin synthesis inhibition and/or (3) via serotonin stimulation of CD8+ subpopulations of activated T cells.
Inventors:
Orn, Thomas Martin
Application Number:
JP51782091A
Publication Date:
April 28, 1994
Filing Date:
September 04, 1991
Export Citation:
Assignee:
Miles Incorporated
International Classes:
A61K31/195; A61K31/00; A61K31/135; A61K31/40; A61K31/435; A61K31/445; A61K31/495; A61K31/505; A61K31/55; A61K39/395; A61K45/00; A61P35/00; A61P43/00; C07K16/28; C07K16/30; A61K38/00; (IPC1-7): A61K45/00; A61K31/195; A61K31/40; A61K31/445; A61K31/495; A61K31/505; A61K39/395
Attorney, Agent or Firm:
Hidekazu Miyoshi (1 outside)