Title:
【発明の名称】pH特性を変更したハロペルオキシダーゼ
Document Type and Number:
Japanese Patent JP2002506638
Kind Code:
A
Abstract:
Variants of a parent vanadium-containing haloperoxidase, which variant has haloperoxidase activity and an altered pH optimum and comprises a mutation in a position corresponding to at least one of the following positions: R490A,L,I,Q,M,E,D; A399G; F397N,Y,E,Q; P395A,S; R360A,L,I,Q,M,E,D; K353Q,M; S402A,T,V,S; D292L; A501S; W350F,Y; V495A,T,V,S; K394A,L,I,Q,M,E,D; wherein the parent haloperoxidase has the amino acid sequence given in SEQ ID No.1, or the parent haloperoxidase has an amino acid sequence which is at least 80 % homologous to SEQ ID No.1.
Inventors:
Allen, Svensen
Lugensen, Luise
Lugensen, Luise
Application Number:
JP2000536834A
Publication Date:
March 05, 2002
Filing Date:
March 16, 1999
Export Citation:
Assignee:
Novo Nordisk Actiesel Scab
International Classes:
D06L4/40; C09D5/14; C09D7/12; C09D201/00; C11D3/386; C12N1/15; C12N1/21; C12N9/08; C12N15/09; C12S3/04; D06M16/00; (IPC1-7): C12N15/09; C09D7/12; C09D201/00; C11D3/386; C12N1/15; C12N1/21; C12N9/08; C12S3/04; D06L3/11; D06M16/00
Attorney, Agent or Firm:
Takashi Ishida (4 others)