【発明の名称】シクロヘキサン誘導体および治療薬としてのその使用

Title:

【発明の名称】シクロヘキサン誘導体および治療薬としてのその使用

Document Type and Number:

Japanese Patent JP2003533509

Kind Code:

A

Abstract:

The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R¹, R², R³, R⁴, R⁵, R⁶, R⁷, R¹³, R¹⁴, R¹⁵, R¹⁶, R¹⁷, R^21aand R^21bare as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

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Inventors:

Castro Pinero, Jose Lewis
Kevin
Elliott, The Eason Machine
Holingworth, Gregory Jiyoung
Sail, Duncan Edward
Swain, Christopher Jiyoung

Application Number:

JP2001584234A

Publication Date:

November 11, 2003

Filing Date:

May 16, 2001

Export Citation:

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Assignee:

Merck Sharp End Dome Limited

International Classes:

C07D295/12; A61K31/165; A61K31/167; A61K31/196; A61K31/223; A61K31/27; A61K31/357; A61K31/40; A61K31/421; A61K31/4355; A61K31/438; A61K31/439; A61K31/444; A61K31/451; A61K31/472; A61K31/495; A61K31/496; A61K31/4985; A61K31/506; A61K31/5375; A61K31/541; A61K31/55; A61P1/08; A61P25/04; A61P25/06; A61P25/22; A61P25/24; A61P29/00; A61P43/00; C07C233/11; C07C233/23; C07C233/32; C07C233/41; C07C237/04; C07C237/06; C07C271/20; C07C271/22; C07C271/24; C07C309/66; C07D207/06; C07D207/08; C07D211/14; C07D211/18; C07D211/22; C07D211/38; C07D211/42; C07D211/44; C07D211/46; C07D211/48; C07D211/58; C07D211/60; C07D211/62; C07D211/74; C07D217/04; C07D241/08; C07D263/22; C07D265/30; C07D275/04; C07D295/135; C07D309/14; C07D317/72; C07D401/04; C07D403/04; C07D403/06; C07D405/04; C07D407/04; C07D417/04; C07D453/06; C07D471/10; C07D487/04; C07D491/048; C07D491/107; C07D491/113; (IPC1-7): C07C233/11; A61K31/165; A61K31/167; A61K31/196; A61K31/223; A61K31/27; A61K31/357; A61K31/40; A61K31/421; A61K31/4355; A61K31/438; A61K31/439; A61K31/444; A61K31/451; A61K31/472; A61K31/495; A61K31/496; A61K31/4985; A61K31/506; A61K31/5375; A61K31/541; A61K31/55; A61P1/08; A61P25/04; A61P25/06; A61P25/22; A61P25/24; A61P29/00; A61P43/00; C07C233/23; C07C233/32; C07C233/41; C07C237/04; C07C237/06; C07C271/20; C07C271/22; C07C271/24; C07C309/66; C07D207/06; C07D207/08; C07D211/14; C07D211/18; C07D211/22; C07D211/38; C07D211/42; C07D211/46; C07D211/48; C07D211/58; C07D211/60; C07D211/62; C07D211/74; C07D217/04; C07D241/08; C07D263/22; C07D265/30; C07D275/04; C07D295/12; C07D309/14; C07D317/72; C07D401/04; C07D403/04; C07D403/06; C07D405/04; C07D417/04; C07D453/06; C07D487/04; C07D491/048; C07D491/107; C07D491/113

Attorney, Agent or Firm:

Yoshio Kawaguchi (4 outside)

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