Title:
【発明の名称】遺伝子又は薬物運搬体としての脂質エマルジョン及び固形脂質微粒子
Document Type and Number:
Japanese Patent JP2002521423
Kind Code:
A
Abstract:
The present invention relates to oil-in-water lipid emulsions composed of non-triglyceride oils and solid lipid nanoparticles (SLN) composed of triglyceride or ethyl stearate used as gene transfection agents and drug delivery systems and method for preparing thereof. The present invention also concerns the method of transferring genes or drugs efficiently into cells by using the lipid emulsions and solid lipid nanoparticles. Also the present invention relates to the method of preparing lipid emulsions containing lipophilic or amphiphilic drugs by using squalene or squalane as the core-oil. The present invention also concerns the method of preparing the solid lipid nanoparticles containing lipophilic or amphiphilic drugs by using ethyl stearate as the core-fat.
Inventors:
John Saeyeon
Kwon Ik Chang
John Hayson
Kwon Ik Chang
John Hayson
Application Number:
JP2000561977A
Publication Date:
July 16, 2002
Filing Date:
July 30, 1999
Export Citation:
Assignee:
Korea Institute of Science and Technologie
International Classes:
A61K9/10; A61K9/107; A61K9/14; A61K9/51; A61K31/196; A61K31/201; A61K31/203; A61K31/5585; A61K31/566; A61K31/57; A61K47/10; A61K47/14; A61K47/18; A61K47/24; A61K47/28; A61K47/30; A61K47/34; A61K47/42; A61K47/44; A61K47/46; A61K48/00; A61P31/12; A61P37/06; C12N15/88; A61K9/127; (IPC1-7): A61K9/107; A61K9/14; A61K31/196; A61K31/201; A61K31/203; A61K31/5585; A61K31/566; A61K31/57; A61K47/10; A61K47/14; A61K47/18; A61K47/24; A61K47/28; A61K47/30; A61K47/34; A61K47/42; A61K47/44; A61K47/46; A61P31/12; A61P37/06
Attorney, Agent or Firm:
Katsuo Naruse (1 person outside)