Title:
【発明の名称】毒物学的に有利に評価されるべきプラスチックを製造するための可塑剤としてのシクロヘキサンポリカルボン酸の使用
Document Type and Number:
Japanese Patent JP2003503526
Kind Code:
A
Abstract:
The invention relates to the use of a cyclohexane polycarboxylic acid or of one of its derivatives, or of a mixture of one or more of said acids as plasticizers in the production of plastics which are rated toxicologically favourable. In animal experiments, using rodents, to which a daily oral dose of 1000 mg/kg body weight of the corresponding cyclohexane polycarboxylic acid, or a derivative thereof, or a mixture of two or more of said acids is administered by oesophageal tube over a period of at least 14 days, said dose, in comparison to untreated control animals, leads neither to a significant increase in the weight of the liver after treatment, nor to a doubling of the specific cyanide-insensitive palmitoyl-CoA oxidase activity, measured in the liver homogenisate.
Inventors:
Melanie Mars-Brunner
Lucian Till
Boris Bright Scheider
Liner otter
Lucian Till
Boris Bright Scheider
Liner otter
Application Number:
JP2001505607A
Publication Date:
January 28, 2003
Filing Date:
June 16, 2000
Export Citation:
Assignee:
BASF Akchen Gezel Shaft
International Classes:
C07C61/08; C07C61/09; C08K5/12; (IPC1-7): C08K5/12
Domestic Patent References:
JPS54163554A | 1979-12-26 | |||
JP2000053874A | 2000-02-22 | |||
JPH0711074A | 1995-01-13 | |||
JPH06306252A | 1994-11-01 | |||
JPH07173342A | 1995-07-11 | |||
JPS58222136A | 1983-12-23 | |||
JP2001526252A | 2001-12-18 |
Foreign References:
US2070770A | 1937-02-16 | |||
US3308086A | 1967-03-07 |
Attorney, Agent or Firm:
Toshio Yano (4 outside)