Title:
【発明の名称】ウィルス、特にレトロウィルスの複製を阻害するためへの“免疫不全ウィルス抑制リンフォカイン(ISL)”の使用
Document Type and Number:
Japanese Patent JPH10507369
Kind Code:
A
Abstract:
An isolated polypeptide which inhibits the replication of retroviruses in peripheral blood lymphocytes and i) is coded by the DNA sequence shown in SEQ ID NO:1 or complementary sequences, ii) is coded by DNA sequences which hybridize with SEQ ID NO:1 or SEQ ID NO:3 under stringent conditions, iii) is coded by DNA sequences which, if there was no degeneracy of the genetic code would hybridize under stringent conditions with the sequences defined in i) to ii), is useful as a therapeutic agent for the treatment of viral infections and benign and malignant proliferation diseases and as a diagnostic agent for said diseases.
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Inventors:
Klute, Reinhard
Michael, Bayer
Karen Metsner
Berner, Albrecht
Michael, Bayer
Karen Metsner
Berner, Albrecht
Application Number:
JP52999496A
Publication Date:
July 21, 1998
Filing Date:
April 04, 1996
Export Citation:
Assignee:
BUNDESREPUBLIK DEUTSCHLAND
International Classes:
G01N33/53; A61K38/00; A61K38/19; A61K48/00; A61P31/12; A61P35/00; A61P37/04; C07K14/52; C07K14/54; C07K16/24; C12N1/21; C12N5/10; C12N15/09; C12N15/19; C12P21/02; C12Q1/68; G01N33/569; G01N33/68; (IPC1-7): C12N15/09; A61K38/00; A61K48/00; C07K14/52; C07K16/24; C12N1/21; C12N5/10; C12P21/02; C12Q1/68; G01N33/53; G01N33/569
Attorney, Agent or Firm:
Takashi Ishida (3 others)