Title:
【発明の名称】チアゾリジンジオン誘導体の早期分娩または授乳期間における子宮収縮を予防するための使用
Document Type and Number:
Japanese Patent JP2002528500
Kind Code:
A
Abstract:
The present invention provides methods of preventing or reducing oxytocin-mediated action by using a thiazolidinedione, such as troglitazone, or thiazolidinedione-like compounds. These methods describe the employment of these compounds alone or in combination with at least one other agent, such as a tocolytic agent. This offers a novel therapeutic regimen for the treatment of oxytocin-mediated actions, for example induction of uterine contractions, prostaglandin release, and milk letdown. Accordingly, conditions such as preterm labor and labor prior to Caesarean delivery can be treated by these methods.
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Inventors:
Copland, John A., The Third
Kirves Elves
Soroff, Melvin
Kirves Elves
Soroff, Melvin
Application Number:
JP2000579222A
Publication Date:
September 03, 2002
Filing Date:
October 29, 1999
Export Citation:
Assignee:
Board Of Regents, The University Of Texas System
International Classes:
A61K31/405; A61K31/426; A61K31/427; A61K31/4422; A61K33/04; A61P15/06; A61P43/00; C07D277/20; C07D277/34; C07D417/12; G01N33/15; G01N33/566; G01N33/50; G01N33/74; (IPC1-7): A61K31/426; A61K31/405; A61K31/427; A61K31/4422; A61K33/04; A61P15/06; A61P43/00; C07D277/34; G01N33/15; G01N33/50; G01N33/566
Attorney, Agent or Firm:
Okuyama Shoichi (2 outside)