Title:
画像処理方法、画像処理装置及びプログラム
Document Type and Number:
Japanese Patent JP7235036
Kind Code:
B2
Abstract:
The present invention addresses the problem of providing an image processing method, an image processing device, and a program capable of quantitatively evaluating the expression level of a specific protein more accurately in a tissue specimen in which fluorescent staining of the specific protein by means of a fluorescent substance, and dye staining for visualizing a cell or a region of interest in a cell, have been carried out in a multiple manner. The image processing method includes: an input step of inputting a fluorescence image and a cell morphology image obtained by capturing images of a tissue specimen in which specific biological material has been stained using a fluorescent substance capable of binding to the specific biological material, and in which a cell has been stained using a dye capable of being observed under visible light; a brightness value calculating step of extracting from the fluorescence image a specific region containing a bright spot, and calculating a brightness value of the specific region; and a brightness value adjusting step of adjusting the brightness value of the specific region on the basis of dye information in the cell morphology image.
Inventors:
Yuichi Ozaki
Application Number:
JP2020504971A
Publication Date:
March 08, 2023
Filing Date:
March 01, 2019
Export Citation:
Assignee:
Konica Minolta Co., Ltd.
International Classes:
G01N33/48; G01N21/64; G01N33/483; G01N33/53; G06T1/00; G06T7/00; G06T7/90
Domestic Patent References:
| JP2015090471A | ||||
| JP2004101354A |
Foreign References:
| WO2017110974A1 | ||||
| WO2017050788A1 | ||||
| WO2017187717A1 | ||||
| WO2012035705A1 |
Attorney, Agent or Firm:
Koyo International Patent Office