To provide an imidazole derivative, a pharmaceutical composition containing the derivative and to provide a compound for treating a disease and condition with unusual cell proliferation and central nervous system.
The compound indicates to have activity inhibiting cdk5, cdk2, and GSK-3. Pharmaceutical composition and method comprising the compound for treating and preventing disease and condition comprising abnormal cell growth, such as cancer, and neurodegenerative disease and condition and those affected by dopamine neurotransmission. Also described are pharmaceutical compositions comprising a compound for treating male fertility and sperm motility; diabetes mellitus; impaired glucose tolerance; metabolic syndrome or syndrome X; polycystic ovary syndrome; adipogenesis and obesity; myogenesis and frailty, for example, age-related decline in physical performance; acute sarcopenia, for example muscle atrophy and/or cachexia associated with burns, bed rest, limb immobilization, or immunodeficiency.
COOPER CHRISTOPHER BLAIR
HELAL CHRISTOPHER JOHN
LAU LIT-FUI
MENNITI FRANK SAMUEL
SANNER MARK ALLEN
SEYMOUR PATRICIA ANN
VILLALOBOS ANABELLA
