Title:
免疫原性HIV組成物および関連する方法
Document Type and Number:
Japanese Patent JP2007523884
Kind Code:
A
Abstract:
The invention provides immunogenic compositions which enhance the duration and strength of the immune response in a mammal. The immunogenic compositions contain an HIV antigen, an immunomer and an adjuvant. The HIV antigen can be a whole-killed HIV virus devoid of outer envelope protein gp120. Alternatively, the HIV antigen can be a whole-killed HIV virus, or a p24 antigen. Also provided are kits, the components of which, when combined, produce the immunogenic compositions of the invention. The invention also provides methods of making the immunogenic compositions, by combining an HIV antigen, an immunomer and optionally an adjuvant. The invention further provides a method of immunizing a mammal, by enhancing an immune response in the mammal by administering to the mammal an immunogenic composition containing an HIV antigen, an immunomer and optionally an adjuvant. Also provided is a method of inhibiting in a mammal by administering to the mammal an immunogenic composition containing an HIV antigen, an immunomer and optionally an adjuvant.
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Inventors:
Moss, Ronald Bee.
Application Number:
JP2006524902A
Publication Date:
August 23, 2007
Filing Date:
August 27, 2004
Export Citation:
Assignee:
The Imune Response Corporation
International Classes:
A61K39/21; A61K31/711; A61K31/7125; A61K31/713; A61K35/76; A61K39/39; A61K48/00; A61P31/12; A61P31/18; A61P37/00; A61P43/00; C12N7/06; C12N
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita