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Title:
IMMUNOGENIC COMPOSITIONS COMPRISING CONJUGATED CAPSULAR SACCHARIDE ANTIGEN AND USES THEREOF
Document Type and Number:
Japanese Patent JP2018135374
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide appropriate protection against Streptococcus pneumoniae serotypes not found in the present pneumococcal 13-valent vaccine while maintaining an immune response against serotypes currently covered by the 13-valent vaccine.SOLUTION: The invention provides an immunogenic compositions comprising a conjugated Streptococcus pneumoniae capsular saccharide antigen (glycoconjugate). In one embodiment, at least one glycoconjugate derived from a Streptococcus pneumoniae serotype not found in Prevnar(R), Synflorix(R) and/or Prevnar13(R) is provided. Also provided is vaccination of human subjects, in particular, infants and elders against pneumococcal infections using the immunogenic composition.SELECTED DRAWING: Figure 1

Inventors:
デイヴィッド クーパー
エミリオ アンソニー エミニ
チアンシン グ
ミングミング ハン
キャサリン ウテ ジャンセン
ラジェシュ クマール カインサン
ジン-フアン キム
アヴァリ クリシュナ プラサド
マイケル ウィリアム プライド
ウェンディ ジョー ワトソン
ユ-イング ヤング
Application Number:
JP2018087041A
Publication Date:
August 30, 2018
Filing Date:
April 27, 2018
Export Citation:
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Assignee:
ファイザー・インク
International Classes:
A61K39/09; A01K67/027; A61K9/08; A61K9/19; A61K39/05; A61K39/08; A61K39/095; A61K39/10; A61K39/102; A61K39/13; A61K39/29; A61K39/385; A61K39/39; A61K47/02; A61K47/12; A61K47/26; A61K47/64; A61P31/04; A61P37/04; C07K2/00; C07K14/02; C07K14/10; C07K14/105; C07K14/195; C07K14/235; C07K14/33; C07K14/34; C12M1/00; C12M1/26
Domestic Patent References:
JP2013518891A2013-05-23
JP2009520761A2009-05-28
JP2009532439A2009-09-10
JP2009520759A2009-05-28
JP2008543905A2008-12-04
JP2008535838A2008-09-04
Foreign References:
WO2012078482A12012-06-14
Other References:
VACCINE, vol. Vol.29,No.48, JPN6017000725, 2011, pages p8870−8876
Attorney, Agent or Firm:
小野 新次郎
山本 修
宮前 徹
中西 基晴
泉谷 玲子