Title:
免疫グロブリン融合タンパク質製剤
Document Type and Number:
Japanese Patent JP2009516692
Kind Code:
A
Abstract:
The present invention provides compositions of Ig fusion proteins, especially compositions including an Ig fusion protein, a bulking agent, a disaccharide, a surfactant, and a buffer. In one aspect, these compositions are stable under long-term storage or at least one freeze/thaw cycle. The invention also provides methods of preparation of the Ig fusion protein compositions. In one aspect, compositions of the invention are lyophilized. In a further aspect, the compositions are lyophilized by a process that includes an annealing step.
Inventors:
Anthony Barry
Thomas Crowley
Daniel Dixon
Jennifer Juneau
Ajay Kumar
Re-li
Nicholas Raksha
Michael shamashkin
Erin sorry
Nicholas Warne
Chandra Web
Thomas Crowley
Daniel Dixon
Jennifer Juneau
Ajay Kumar
Re-li
Nicholas Raksha
Michael shamashkin
Erin sorry
Nicholas Warne
Chandra Web
Application Number:
JP2008541422A
Publication Date:
April 23, 2009
Filing Date:
November 21, 2006
Export Citation:
Assignee:
Wyeth
International Classes:
A61K47/02; A61K47/48; A61K47/18; A61K47/26; A61K47/34
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita