Title:
可溶性エポキシド加水分解酵素の改良された阻害剤
Document Type and Number:
Japanese Patent JP2008517072
Kind Code:
A
Abstract:
Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
Inventors:
Hammock Bruce Dee.
Kim In-H
Morisou Christoph
Takuho Watanabe
Newman John W.
Jones paul
One Sun Hee
Wet stone pole
Kim In-H
Morisou Christoph
Takuho Watanabe
Newman John W.
Jones paul
One Sun Hee
Wet stone pole
Application Number:
JP2007538151A
Publication Date:
May 22, 2008
Filing Date:
October 20, 2005
Export Citation:
Assignee:
The Legends of the University of California
International Classes:
C07C233/06; A61K31/17; A61K31/18; A61K31/197; A61K31/198; A61K31/20; A61K31/221; A61K31/277; A61K31/401; A61K31/405; A61K31/417; A61K31/4172; A61K31/7028; A61P3/10; A61P9/08; A61P9/12; A61P11/00; A61P11/06; A61P11/16; A61P13/12; A61P15/10; A61P19/02; A61P29/00; A61P43/00; C07C233/08; C07C233/11; C07C233/15; C07C233/26; C07C233/48; C07C233/60; C07C235/14; C07C235/36; C07C237/20; C07C271/24; C07C271/36; C07C275/10; C07C275/26; C07C275/28; C07C275/30; C07C275/42; C07C311/04; C07C311/40; C07C311/41; C07C311/51; C07C323/44; C07D207/16; C07D209/20; C07D233/64; C07H13/04; C12N9/99; G01N21/78; C12N9/14
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Other References:
JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, no. 8, JPN6011000349, 2004, pages 2110 - 2122, ISSN: 0001819469
BIOCHEMICAL PHARMACOLOGY, vol. 63, no. 9, JPN6011000350, 2002, pages 1599 - 1608, ISSN: 0001819470
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, no. 11, JPN6011000352, 2000, pages 2663 - 2673, ISSN: 0001819471
SYNLETT, JPN6011000353, 1994, pages 349 - 350, ISSN: 0001819472
BIOCHEMICAL PHARMACOLOGY, vol. 63, no. 9, JPN6011000350, 2002, pages 1599 - 1608, ISSN: 0001819470
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 8, no. 11, JPN6011000352, 2000, pages 2663 - 2673, ISSN: 0001819471
SYNLETT, JPN6011000353, 1994, pages 349 - 350, ISSN: 0001819472
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi