Title:
改善された薬剤候補およびその調製法
Document Type and Number:
Japanese Patent JP2007516940
Kind Code:
A
Abstract:
The present invention is directed to methods of preparation of sulfonate derivatized compounds, e.g., 3-amino-l-propanesulfonic acid and 1,3-propanedisulfonic acid disodium salt with increased purity, with reduced potential for toxic by-products, and that are pharmaceutically useful, e.g., for the treatment of amyloidosis.
More Like This:
Inventors:
Conscious
Mignaud David
Wu Shinfu
Mignaud David
Wu Shinfu
Application Number:
JP2006516612A
Publication Date:
June 28, 2007
Filing Date:
June 21, 2004
Export Citation:
Assignee:
Neurochem (International) Limited
International Classes:
C07C303/02; A61K31/10; A61K31/13; A61K31/131; A61K31/135; A61K31/137; A61K31/155; A61K31/165; A61K31/17; A61K31/198; A61K31/36; A61K31/41; A61K31/4164; A61K31/4365; A61K31/437; A61K31/439; A61K31/44; A61K31/4418; A61K31/4425; A61K31/451; A61K31/47; A61K31/495; A61P3/10; A61P9/00; A61P9/10; A61P21/00; A61P25/28; A61P29/00; A61P43/00; C07C303/22; C07C303/32; C07C309/14; C07C309/15; C07C335/32; C07D207/325; C07D211/40; C07D211/52; C07D211/64; C07D211/70; C07D213/04; C07D217/04; C07D217/10; C07D221/04; C07D233/54; C07D233/60; C07D257/04; C07D295/08; C07D295/088; C07D317/58; C07D453/02; C07D471/04; C07D495/04; C07C309/05; C07D207/32
Domestic Patent References:
| JPH05239013A | 1993-09-17 | |||
| JPH03236367A | 1991-10-22 | |||
| JPH01313458A | 1989-12-18 | |||
| JP2003517458A | 2003-05-27 | |||
| JP2002502871A | 2002-01-29 | |||
| JPH04210953A | 1992-08-03 | |||
| JPS57150655A | 1982-09-17 | |||
| JPS554309A | 1980-01-12 | |||
| JPS4844413A | 1973-06-26 | |||
| JPS4814621A | ||||
| JP2003532656A | 2003-11-05 |
Foreign References:
| US4085134A | 1978-04-18 | |||
| GB764340A | 1956-12-28 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi