IMPROVED REAGENT FOR CANNABINOID IMMUNOASSAY

Title:

IMPROVED REAGENT FOR CANNABINOID IMMUNOASSAY

Document Type and Number:

Japanese Patent JP2009051839

Kind Code:

A

Abstract:

To provide an immunoassay reagent containing an anti-cannabinoid antibody which recognizes the major metabolites of the active ingredient THC of marijuana as much as possible and has a wide range of specificity.

A new benzopyran derivative which has a chemical linker to easily conjugate with a protein and is represented by formula (1) (wherein R1 is an alkyl group; R2 and R3 are each a lower hydrocarbon group which may have a substituent; and a, b, and c are each a single bond or a double bond) is synthesized and allowed to conjugate with a proteinaceous carrier to prepare an immunogen, and this immunogen is administered to an animal, and from splenocytes of the immunized animal, an anti-cannabinoid antibody having an average cross-reactivity of at least about 80% to all of the major THC metabolites is obtained.

More Like This:

JP4494974	P153 and p156 antigens and their use for immunodiagnosis of canine and human aerrichia
WO/1993/025665	RECOMBINANT HERPESVIRUS OF TURKEYS AND USES THEREOF
JP2015042166	VACCINES AND VACCINE COMPONENTS FOR INHIBITION OF MICROBIAL CELLS

Inventors:

HUI RAYMOND ALBERT
ROSEN STEVEN MARK
SALMONE SALVATORE JOSEPH

Application Number:

JP2008217504A

Publication Date:

March 12, 2009

Filing Date:

August 27, 2008

Export Citation:

Click for automatic bibliography generation Help

Assignee:

HOFFMANN LA ROCHE

International Classes:

A61K39/00; C07D311/20; A61K39/395; G01N33/53; C07D311/58; C07D311/70; C07D405/12; C07D417/12; C07K16/00; G01N33/531; G01N33/94; C12P21/08

Domestic Patent References:

JPH01273582A	1989-11-01
JPH06211867A	1994-08-02
JPS63192770A	1988-08-10
JPS63216880A	1988-09-09

Foreign References:

US2354492A

1944-07-25

Attorney, Agent or Firm:

Hideto Asamura
Hajime Asamura
Naganuma Akio

Previous Patent: JP2009051838

Next Patent: POWDER PROCESSING WITH PRESSURIZED GASEOUS FLUID