Title:
IMPROVEMENT IN IMMOBILIZED BIOLOGICAL COMPONENTS
Document Type and Number:
Japanese Patent JP2023017012
Kind Code:
A
Abstract:
To provide a medical device having a combination of drug eluting properties and thromboresistance.SOLUTION: The device has a surface comprising a layered coating where the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da, (ii) a total molecular weight of 1,500 to 1,000,000 Da, (iii) a ratio of the total molecular weight to the core moiety molecular weight of at least 80:1, and (iv) functional end groups, where one or more of the functional end groups have an anti-coagulant substance covalently attached thereto.SELECTED DRAWING: None
Inventors:
Carlin Leontein
Per Antoni
Daniel Nystrom
Paul Begovac
Christophe Pietrzak
Per Antoni
Daniel Nystrom
Paul Begovac
Christophe Pietrzak
Application Number:
JP2022196345A
Publication Date:
February 02, 2023
Filing Date:
December 08, 2022
Export Citation:
Assignee:
W.L. GORE & ASSOCIATES, INCORPORATED
International Classes:
A61L27/34; A61L29/08; A61L31/10; A61L33/00; A61L33/10
Attorney, Agent or Firm:
Aoki Atsushi
Shinji Mihashi
Satoshi Deno
Atsushi Ebiya
Nakajima Masaru
Shinji Mihashi
Satoshi Deno
Atsushi Ebiya
Nakajima Masaru