Title:
INDOLINE DERIVATIVE
Document Type and Number:
Japanese Patent JP2016108257
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide: a compound or a pharmacologically acceptable salt thereof which inhibits a retinoic acid receptor-related orphan receptor and, due to suppression of Th-17 cell differentiation and/or suppression of IL-17 production, is effective for treatment and/or prevention of psoriasis, multiple sclerosis, rheumatic arthritis, inflammatory bowel disease, Sjogren's syndrome, systemic lupus erythematosus, chronic obstructive pulmonary disease, asthma, or colon cancer; and a pharmaceutical composition containing the compound.SOLUTION: Provided are a compound represented by the following formula or a pharmacologically acceptable salt thereof, and a pharmaceutical composition containing the compound.SELECTED DRAWING: None
Inventors:
NAGAMOCHI MASATOSHI
GOTANDA TAKENORI
NOGUCHI TETSUJI
GOTO YASUHARU
SASAKI JUNKO
TORIHATA MUNEFUMI
YOSHINO TOSHIJI
ISOBE TAKASHI
GOTANDA TAKENORI
NOGUCHI TETSUJI
GOTO YASUHARU
SASAKI JUNKO
TORIHATA MUNEFUMI
YOSHINO TOSHIJI
ISOBE TAKASHI
Application Number:
JP2014245409A
Publication Date:
June 20, 2016
Filing Date:
December 03, 2014
Export Citation:
Assignee:
DAIICHI SANKYO CO LTD
International Classes:
C07D209/04; A61K31/404; A61K31/405; A61K31/4155; A61K31/4178; A61K31/4184; A61K31/4188; A61K31/437; A61K31/4412; A61K31/4439; A61K31/454; A61K31/4725; A61K31/498; A61K31/5377; A61K31/5383; A61P1/04; A61P11/00; A61P11/06; A61P17/06; A61P19/02; A61P25/00; A61P29/00; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07D209/42; C07D401/06; C07D401/12; C07D403/12; C07D405/12; C07D405/14; C07D471/04; C07D487/04; C07D498/04
Attorney, Agent or Firm:
Kimiki Ishibashi
Noriko Kitano
Toshiyasu Takemoto
Hironobu Kodama
Reiko Kanehara
Noriko Kitano
Toshiyasu Takemoto
Hironobu Kodama
Reiko Kanehara