Title:
イソブチルメチル1,4-ジヒドロ-2,6-ジメチル-4-(2-ニトロフェニル)-3,5-ピリジンジカルボン酸塩(ニソルジピン)の合成のための工業的製法
Document Type and Number:
Japanese Patent JP2006512287
Kind Code:
A
Abstract:
Synthetic process of isobutyl methyl 1,4,-dihydro-2,6-dimethyl-4-(2-nitrophenyl)3,5-pyridine dicarboxylate (Nisoldipine) comprising on the reaction of isobutyl 2-(2-nitrobenzylidene)acetoacetate with methyl 3-aminocrotonate in an apolar solvent.
Inventors:
Ferrari Massimo
Gezzi Marcello
Alberelli manuel
Ambrosini Alberto
Gezzi Marcello
Alberelli manuel
Ambrosini Alberto
Application Number:
JP2004516691A
Publication Date:
April 13, 2006
Filing Date:
June 26, 2003
Export Citation:
Assignee:
Elegile Societa Peratini
International Classes:
C07D211/90; C07C201/12; C07C205/56; C07B61/00
Attorney, Agent or Firm:
Jyohei Yamashita