Title:
単位用量懸濁液から調製されるスルホアルキルエーテルシクロデキストリンおよびコルチコステロイドを含む吸入製剤
Document Type and Number:
Japanese Patent JP2007517068
Kind Code:
A
Abstract:
An inhalable formulation comprising SAE-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueous solution, however, it can be stored as a dry powder, ready-to-use solution, or concentrated composition. The formulation is employed in an improved nebulization system for administering corticosteroid by inhalation. SAE-CD present in the formulation significantly enhances the chemical stability of budesonide. A method of administering the formulation by inhalation is provided. The formulation can also be administered by conventional nasal delivery apparatus.
Inventors:
Rupert Oh Zimmerer
James Dee Pipkin
Diane Oh Thompson
Gerold El Mosher
James Dee Pipkin
Diane Oh Thompson
Gerold El Mosher
Application Number:
JP2006547614A
Publication Date:
June 28, 2007
Filing Date:
December 31, 2004
Export Citation:
Assignee:
Sidex Incorporated
International Classes:
A61K31/573; A61K9/00; A61K9/08; A61K9/12; A61K9/14; A61K9/72; A61K31/16; A61K31/57; A61K31/58; A61K31/715; A61K45/00; A61K47/40; A61K47/48; A61P11/06; A61P43/00; C08B37/16
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa