Title:
AKT活性の阻害剤
Document Type and Number:
Japanese Patent JP4673300
Kind Code:
B2
Abstract:
The present invention is directed to compounds which contain a heterocyclic triazine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
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Inventors:
Bilodo, Mark Tay
Linsley, Craig Davryu
Chiao, Chijiang
Linsley, Craig Davryu
Chiao, Chijiang
Application Number:
JP2006513154A
Publication Date:
April 20, 2011
Filing Date:
April 20, 2004
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D401/14; A61K31/53; A61P35/00; C07D253/06; C07D405/14; C07D409/14; C07D413/14; C07D417/14; A61K31/5377; A61P3/10; A61P5/48; A61P9/00; A61P11/06; A61P29/00; A61P37/06; A61P37/08; A61P43/00; A61K
Foreign References:
| WO2003084473A2 | ||||
| WO2002083138A1 | ||||
| WO2002083064A2 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura