Inhibitor of C-JUN-N-end kinase (JNK) - DANA-FARBER CANCER INSTITUTE, INC.

Title:

Inhibitor of C-JUN-N-end kinase (JNK)

Document Type and Number:

Japanese Patent JP6262383

Kind Code:

B2

Abstract:

The present invention provides novel compounds according to Formula (I):where Ring A, Ring B, X, L₁, L₂, R^A, R^C, R^D, R^E, m, n, and p are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of human diseases associated with kinase activity, for example, proliferative diseases, neurodegenerative diseases, metabolic disorders, inflammatory diseases, and cardiovascular diseases.

Inventors:

Grey, nathaniel
Chang, Tin Fu

Application Number:

JP2017042266A

Publication Date:

January 17, 2018

Filing Date:

March 06, 2017

Export Citation:

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Assignee:

DANA-FARBER CANCER INSTITUTE, INC.

International Classes:

C07D471/04; A61K31/506; A61P3/00; A61P3/10; A61P19/02; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P43/00; C07D403/04

Domestic Patent References:

JP2008500320A

Foreign References:

WO2002083653A1

Attorney, Agent or Firm:

Kiyoji Kuzuwa

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