Title:
IAPの阻害剤
Document Type and Number:
Japanese Patent JP4691549
Kind Code:
B2
Abstract:
Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula IV:
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Inventors:
Mark G. Palermo
Susir Kumar Sharma
Christopher Strobe
Run-Min Wan
Lee Sawell
Jang Yang Lin
Chen Chuolian
One Yapin
Yang Fan
Wojusieck Lorna
Ryu Gun
Mark G. Charest
He Feng
Susir Kumar Sharma
Christopher Strobe
Run-Min Wan
Lee Sawell
Jang Yang Lin
Chen Chuolian
One Yapin
Yang Fan
Wojusieck Lorna
Ryu Gun
Mark G. Charest
He Feng
Application Number:
JP2007506718A
Publication Date:
June 01, 2011
Filing Date:
April 06, 2005
Export Citation:
Assignee:
Novartis Age
International Classes:
C07K5/062; A61K31/40; A61K31/4025; A61K31/437; A61K31/4745; A61K31/55; C07D207/06; C07D207/08; C07D207/09; C07D207/16; C07D401/04; C07D401/12; C07D403/04; C07D403/06; C07D403/12; C07D405/10; C07D405/12; C07D409/12; C07D413/04; C07D413/14; C07D417/04; C07D471/02; C07D471/04; C07D487/04; A61K38/00; A61P35/00
Foreign References:
| WO2004005248A1 | ||||
| WO2001090070A2 |
Other References:
J. Biol. Chem.,2002年11月15日,Vol.277, No.46,pp.44236-44243
Biochemistry,2002年 6月11日,Vol.41, No.23,pp.7344-7349
Mol. Cell.,2001年 7月,Vol.8, No.1,pp.95-104
J. Med. Chem.,1992年10月30日,Vol.35, No.22,pp.4195-4204
Biochemistry,2002年 6月11日,Vol.41, No.23,pp.7344-7349
Mol. Cell.,2001年 7月,Vol.8, No.1,pp.95-104
J. Med. Chem.,1992年10月30日,Vol.35, No.22,pp.4195-4204
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai
Takuji Yamada
Michiko Matsutani
Mitsutaka Iwasaki
Yasushi Ochiai