Title:
グルココルチコイド受容体の阻害剤
Document Type and Number:
Japanese Patent JP6801093
Kind Code:
B2
Abstract:
The present invention relates generally to compositions and methods for treating cancer and hypercortisolism. Provided herein are substituted steroidal derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of glucocorticoid receptors. Furthermore, the subject compounds and compositions are useful for the treatment of cancer.
Inventors:
Sun, dachin
Maggie, Lawrence Earl.
Doo, Shaohui
Dus, Ryu Shen
Yang, Shwe Lei
Ryu, Yosap
Extero Witz, John
Medina, Julio Sea.
Fantin, Valeria Earl.
Elephant, high inn
Barbus, Minna De La Lae
Maggie, Lawrence Earl.
Doo, Shaohui
Dus, Ryu Shen
Yang, Shwe Lei
Ryu, Yosap
Extero Witz, John
Medina, Julio Sea.
Fantin, Valeria Earl.
Elephant, high inn
Barbus, Minna De La Lae
Application Number:
JP2019517236A
Publication Date:
December 16, 2020
Filing Date:
October 06, 2017
Export Citation:
Assignee:
Orick Pharmaceuticals, Inc.
International Classes:
C07J41/00; A61K31/569; A61K45/00; A61P13/08; A61P15/00; A61P35/00; A61P43/00
Domestic Patent References:
| JP9104696A | ||||
| JP2003119154A | ||||
| JP2001508079A |
Foreign References:
| US20040180869 | ||||
| US6512130 | ||||
| US5843933 | ||||
| US5728689 |
Other References:
Steroids,2000年,65,157-162
Steroids,2014年,92,45-55
Steroids,2014年,92,45-55
Attorney, Agent or Firm:
Kazuhiro Kiyohara