INHIBITOR OF HUMAN PLASMIN DERIVED FROM KUNITZ DOMAIN

Title:

INHIBITOR OF HUMAN PLASMIN DERIVED FROM KUNITZ DOMAIN

Document Type and Number:

Japanese Patent JP2012111779

Kind Code:

A

Abstract:

To provide novel plasmin inhibitors.

This invention relates to a polypeptyde obtained by modifying a first Kunitz domain (K1) of a lipoprotein-associated coagulation inhibitor (LACI).

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Inventors:

MARKLAND WILLIAM
LADNER ROBERT CHARLES

Application Number:

JP2012044051A

Publication Date:

June 14, 2012

Filing Date:

February 29, 2012

Export Citation:

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Assignee:

DYAX CORP

International Classes:

C07K14/81; A61K38/00; C12N15/09; A61K38/55; A61K38/57; A61K51/00; A61P7/04; C04B35/593; C12N9/68; C12Q1/37; C12Q1/56

Domestic Patent References:

JP4137997B2

2008-08-20

Foreign References:

WO1993014122A1

1993-07-22

Other References:

JPN6007016035; Ｂｉｏｌ．　Ｃｈｅｍ．　Ｈｏｐｐｅ-Ｓｅｙｌｅｒ，　３６７（１１），　１９８６，　ｐｐ１１６７-１１７６
JPN6007016033; Ｅｕｒ．　Ｊ．　Ｂｉｏｃｈｅｍ．，　２１４（１），　１９９３，　ｐｐ２７１-２７９

Attorney, Agent or Firm:

Okabe
Masao Okabe
Shinichi Usui
Norimichi Takanashi
Honda Aki

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