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Title:
ミクロソーム・トリグリセリド転移プロテインの抑制剤および方法
Document Type and Number:
Japanese Patent JP4036244
Kind Code:
B2
Abstract:
Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure defined herein.

Inventors:
Wetello, John Earl the Second
Sharp, Dal Young
Greg, Richard Yee
Biller, Scott A
Dickson, John A
Lawrence, Earl Michael
Magnin, David Earl
Poss, Michael A.
Roble, Jeffrey A.
Salkey, Richard Bee
Tino, Joseph A.
Lawson, John Yee
Horaba, Henry M
Partyka, Richard A.
Application Number:
JP52567996A
Publication Date:
January 23, 2008
Filing Date:
February 01, 1996
Export Citation:
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Assignee:
The Trusties of the University of Pennsylvania
International Classes:
C07D211/58; A61K31/4427; A61K31/443; A61K31/4433; A61K31/445; A61K31/4468; A61K31/47; A61K31/495; A61K31/505; A61K31/52; A61K31/535; A61P3/06; A61P9/10; A61P43/00; C07D211/00; C07D211/56; C07D211/60; C07D211/94; C07D211/98; C07D215/38; C07D217/00; C07D217/22; C07D221/16; C07D241/04; C07D401/00; C07D401/04; C07D401/12; C07D401/14; C07D405/06; C07D405/12; C07D409/06; C07D409/12; C07D409/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D419/12; C07D473/00; A61K31/452; A61K31/4525; A61K31/4535; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/501; A61K31/502; A61K31/517; A61K31/5355; A61K31/5377; A61P1/18; A61P3/04; A61P3/10
Domestic Patent References:
JP6038761A
JP47006026A
JP5208974A
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Minato Saito
Nagatoshi Shinagawa