Title:
ミクロソーム・トリグリセリド転移プロテインの抑制剤および方法
Document Type and Number:
Japanese Patent JP4036244
Kind Code:
B2
Abstract:
Compounds are provided which inhibit microsomal triglyceride transfer protein and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases. The compounds have the structure defined herein.
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Inventors:
Wetello, John Earl the Second
Sharp, Dal Young
Greg, Richard Yee
Biller, Scott A
Dickson, John A
Lawrence, Earl Michael
Magnin, David Earl
Poss, Michael A.
Roble, Jeffrey A.
Salkey, Richard Bee
Tino, Joseph A.
Lawson, John Yee
Horaba, Henry M
Partyka, Richard A.
Sharp, Dal Young
Greg, Richard Yee
Biller, Scott A
Dickson, John A
Lawrence, Earl Michael
Magnin, David Earl
Poss, Michael A.
Roble, Jeffrey A.
Salkey, Richard Bee
Tino, Joseph A.
Lawson, John Yee
Horaba, Henry M
Partyka, Richard A.
Application Number:
JP52567996A
Publication Date:
January 23, 2008
Filing Date:
February 01, 1996
Export Citation:
Assignee:
The Trusties of the University of Pennsylvania
International Classes:
C07D211/58; A61K31/4427; A61K31/443; A61K31/4433; A61K31/445; A61K31/4468; A61K31/47; A61K31/495; A61K31/505; A61K31/52; A61K31/535; A61P3/06; A61P9/10; A61P43/00; C07D211/00; C07D211/56; C07D211/60; C07D211/94; C07D211/98; C07D215/38; C07D217/00; C07D217/22; C07D221/16; C07D241/04; C07D401/00; C07D401/04; C07D401/12; C07D401/14; C07D405/06; C07D405/12; C07D409/06; C07D409/12; C07D409/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D419/12; C07D473/00; A61K31/452; A61K31/4525; A61K31/4535; A61K31/454; A61K31/4545; A61K31/4709; A61K31/4725; A61K31/496; A61K31/497; A61K31/501; A61K31/502; A61K31/517; A61K31/5355; A61K31/5377; A61P1/18; A61P3/04; A61P3/10
Domestic Patent References:
JP6038761A | ||||
JP47006026A | ||||
JP5208974A |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Minato Saito
Nagatoshi Shinagawa
Samejima Mutsumi
Minato Saito
Nagatoshi Shinagawa