Title:
INJECTABLE DEPOT COMPOSITION AND USE THEREOF
Document Type and Number:
Japanese Patent JP2010189407
Kind Code:
A
Abstract:
To provide a depot composition which is injected into a desired position in a patient's body to form a graft, which continuously produces a valuable agent.
The injectable depot composition includes a bioerodible, biocompatibile polymer; an effective amount of aromatic alcohol which has a water miscibility of ≤7 wt.% at 25°C and plasticizes the polymer to form a gel with it; and the valuable agent. The composition may include an ester of an aromatic acid or an aromatic ketone.
Inventors:
CHEN GUOHUA
HOUSTON PAUL RICKY
KLEINER LOTHAR WALTHER
WRIGHT JEREMY CORWIN
HOUSTON PAUL RICKY
KLEINER LOTHAR WALTHER
WRIGHT JEREMY CORWIN
Application Number:
JP2010085269A
Publication Date:
September 02, 2010
Filing Date:
April 01, 2010
Export Citation:
Assignee:
DURECT CORP
International Classes:
A61K9/06; A61K9/00; A61K31/56; A61K38/00; A61K38/22; A61K38/43; A61K45/00; A61K47/08; A61K47/10; A61K47/14; A61K47/30; A61K47/34; A61K47/36; A61K47/38; A61K47/42; A61M37/00; A61P1/00; A61P3/00; A61P3/10; A61P5/00; A61P9/00; A61P19/00; A61P19/02; A61P21/00; A61P25/00; A61P25/02; A61P37/00
Domestic Patent References:
JPH08501064A | 1996-02-06 | |||
JP2004536036A | 2004-12-02 | |||
JP2001509146A | 2001-07-10 |
Foreign References:
WO2000074650A2 | 2000-12-14 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Eiichi Arai
Ishii Teiji
Satoshi Fujita
Eiichi Arai