Title:
第3アンモニウム基を有する(メタ)アクリレート-コポリマーのための射出成形法
Document Type and Number:
Japanese Patent JP4828758
Kind Code:
B2
Abstract:
The invention relates to a process for making molded articles by means of injection molding with the process steps of a) melting of a (meth)acrylate copolymer, which is composed of 30 to 80 wt % of radical-polymerized C1 to C4 alkyl esters of acrylic or methacrylic acid and 70 to 20 wt % of (meth)acrylate monomers with a tertiary ammonium group in the alkyl residue, wherein the (meth)acrylate copolymer is present in a mixture with 1 to 70 wt % of a plasticizer and a desiccant in the ratio of 1:1 to 1:20 and also with 0.05 to 5 wt % of a release agent, and further standard additives or adjuvants and if necessary even a pharmaceutical active principle can also be present in the mixture, and before the mixture is melted it has a content of more than 0.5 wt % of low-boiling constituents with a vapor pressure of at least 1.9 bar at 120° C., b) degassing of the mixture in the thermoplastic condition at temperatures of at least 120° C., whereby the content of low-boiling constituents with a vapor pressure of at least 1.9 bar at 120° C. is lowered to at most 0.5 wt % and c) injection of the melted and degassed mixture into the mold cavity of an injection-molding die, wherein the mold cavity has a temperature which lies at least 10° C. below the glass transition temperature of the (meth)acrylate copolymer, cooling of the melt mixture and removal of the obtained molded article from the mold.
Inventors:
Hans-Ulrich Peterite
Thomas Beckert
Manfred Asmus
Werner Hess
Wolfgang Fuchs
Hartmut Shikowski
Thomas Beckert
Manfred Asmus
Werner Hess
Wolfgang Fuchs
Hartmut Shikowski
Application Number:
JP2001541484A
Publication Date:
November 30, 2011
Filing Date:
November 29, 2000
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
A61J3/07; A61K9/16; B29C45/00; A61K9/20; A61K9/22; A61K9/48; A61K9/52; A61K9/58; B29D99/00
Domestic Patent References:
| JPH08245422A | 1996-09-24 | |||
| JPH01290408A | 1989-11-22 | |||
| JPH0873378A | 1996-03-19 | |||
| JPS56136341A | 1981-10-24 | |||
| JPS59198110A | 1984-11-09 | |||
| JPS611624A | 1986-01-07 |
Attorney, Agent or Firm:
Toshio Yano
Takuya Kuno
Takahashi
Kimihiro Hoshi
Hiroyasu Ninomiya
Einzel Felix-Reinhard
Takuya Kuno
Takahashi
Kimihiro Hoshi
Hiroyasu Ninomiya
Einzel Felix-Reinhard