Title:
無機塩類タンパク複合医療機器
Document Type and Number:
Japanese Patent JP6976501
Kind Code:
B2
Abstract:
A medical instrument in which an inorganic salt solid such as apatite into which a peptide hormone or the like is embedded is placed so that a metal or the like is coated therewith, in which the inorganic salt solid is provided by controlled delay co-precipitation or the like in an unstable supersaturated calcium phosphate solution, and the medical instrument is exposed to ionizing radiation at a dose sufficient for sterilization.
Inventors:
Tadao Ohno
Mayu Yasunaga
Atsuo Ito
Togawa Tomo
Kobayashi Fumiko
Mayu Yasunaga
Atsuo Ito
Togawa Tomo
Kobayashi Fumiko
Application Number:
JP2020569704A
Publication Date:
December 08, 2021
Filing Date:
January 30, 2020
Export Citation:
Assignee:
Cell Medicine Co., Ltd.
National Institute of Advanced Industrial Science and Technology
University of Tsukuba
National Institute of Advanced Industrial Science and Technology
University of Tsukuba
International Classes:
A61L27/20; A61B17/72; A61B17/86; A61C8/00; A61F2/28; A61F2/30; A61L27/02; A61L27/04; A61L27/06; A61L27/10; A61L27/12; A61L27/30; A61L27/32; A61L27/42; A61L27/50; A61L27/54
Domestic Patent References:
| JP2009018086A | ||||
| JP2012521776A | ||||
| JP11506360A |
Foreign References:
| WO2006004778A1 |
Other References:
菅 幹雄 ほか,FGF活性の細胞外基質による制御 -FGF/ヘパリン/FGFレセプター複合体-,Tiss. Cul. Res. Commun.,1992年,Vol.11,pp.345-352
TSURUSHIMA, H. et al.,Enhanced bone formation using hydroxyapatite ceramic coated with fibroblast growth factor-2,Acta Biomaterialia,2010年,Vol.6,pp.2751-2759
MUTSUZAKI, H. et al.,Fibroblast Growth Factor-2-Apatite Composite Layers on Titanium Screws to Reduce Pin Tract Infection,J. Biomed. Mater. Res. Part B: Appl. Biomater.,2008年,Vol. 86B,pp.365-374
YANAGISAWA, Y. et al.,Initial clinical trial of pins coated with fibroblast growth factor-2-apatite composite layer in ext,Journal of Orthopaedics,2018年12月20日,Vol.16,pp.69-73
TSURUSHIMA, H. et al.,Enhanced bone formation using hydroxyapatite ceramic coated with fibroblast growth factor-2,Acta Biomaterialia,2010年,Vol.6,pp.2751-2759
MUTSUZAKI, H. et al.,Fibroblast Growth Factor-2-Apatite Composite Layers on Titanium Screws to Reduce Pin Tract Infection,J. Biomed. Mater. Res. Part B: Appl. Biomater.,2008年,Vol. 86B,pp.365-374
YANAGISAWA, Y. et al.,Initial clinical trial of pins coated with fibroblast growth factor-2-apatite composite layer in ext,Journal of Orthopaedics,2018年12月20日,Vol.16,pp.69-73
Attorney, Agent or Firm:
Hidewa Patent Office
Patent Service Corporation Patent Office Sykes
Patent Service Corporation Patent Office Sykes