Title:
INTEGRATED ANALYZING APPARATUS, AND MANUFACTURING METHOD AND ANALYZING TECHNIQUE RELATED TO THE SAME
Document Type and Number:
Japanese Patent JP2015096854
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide an apparatus that restrains, by reducing background signals, quenching of florescent pigment molecules exposed in the apparatus.SOLUTION: In an apparatus comprising a first substrate and a second substrate, the first and second substrates define a channel arranged between the substrates, and at least one of the first or second substrates partially makes possible passage of electromagnetic radiation having at least one wavelength of a range from about 10 nm to about 2500 nm. A first film is disposed over at least part of the first substrate, the second substrate or both, and at least part of the first film defines at least part of the channel arranged at least between the first and second substrates, and the first film, when the apparatus is irradiated with the electromagnetic radiation having a wavelength of the range from about 10 nm to about 2500 nm, can reduce the background signals of the apparatus compared with an apparatus of the same type except that the first film is absent.
More Like This:
| JPS5342795 | NOZZLE FOR GATHERING BLOOD SERUM |
| JPH0348770 | BIOCHEMICAL ANALYSIS APPARATUS |
Inventors:
CAO HAN
AUSTIN MICHAEL D
PARIKSHIT A DESHPANDE
MARK KUNKEL
ALEXEY Y SHARONOV
MICHAEL KOCHERSPERGER
AUSTIN MICHAEL D
PARIKSHIT A DESHPANDE
MARK KUNKEL
ALEXEY Y SHARONOV
MICHAEL KOCHERSPERGER
Application Number:
JP2014233087A
Publication Date:
May 21, 2015
Filing Date:
November 17, 2014
Export Citation:
Assignee:
BIONANOMATRIX LLC
International Classes:
G01N35/10; B81B1/00; B81C3/00; G01N37/00
Domestic Patent References:
| JP2007278906A | 2007-10-25 | |||
| JP2005533636A | 2005-11-10 | |||
| JP2000111477A | 2000-04-21 | |||
| JP2005505754A | 2005-02-24 | |||
| JPH07506430A | 1995-07-13 | |||
| JP2002243734A | 2002-08-28 |
Foreign References:
| WO2006101851A2 | 2006-09-28 | |||
| US20060065528A1 | 2006-03-30 | |||
| WO2006117541A1 | 2006-11-09 |
Other References:
E. ABAD ET AL.: "Design and fabrication using nanoimprint lithography of a nanofluidic device for DNA stretching appl", MICROELECTRONIC ENGINEERING, JPN6015042787, 8 January 2008 (2008-01-08), pages 818 - 821, ISSN: 0003181995
HAN CAO: "Gradient nanostructures for interfacing microfluidics and nanofluidics", GRADIENT NANOSTRUCTURES FOR INTERFACING MICROFLUIDICS AND NANOFLUIDICS, vol. 81, no. 16, JPN6015042789, 14 October 2002 (2002-10-14), pages 3058 - 3060, XP012032222, ISSN: 0003182000, DOI: 10.1063/1.1515115
J. T. MANNION,: "Conformational Analysis of Single DNA Molecules Undergoing Entropically Induced Motion in Nanochanne", BIOPHYSICAL JOURNAL, vol. 90, JPN6013004236, June 2006 (2006-06-01), pages 4538 - 4545, XP007910275, ISSN: 0003181996, DOI: 10.1529/biophysj.105.074732
Y.H. CHO: "Fabrication of silicon dioxide nanochannel arrays without nanolithography for manipulation of DNA mo", MICROELECTRONIC ENGINEERING, vol. 85, JPN6015001389, 13 March 2008 (2008-03-13), pages 1275 - 1277, ISSN: 0003181997
N. KAJI ET AL.: "Separation of Long DNA Molecules by Quartz Nanopillar Chips under a Direct Current Electric Field", ANAL. CHEM., vol. 76, no. 1, JPN6014029869, 1 January 2004 (2004-01-01), pages 15 - 22, XP001047450, ISSN: 0003181998, DOI: 10.1021/ac030303m
C. H. RECCIUS ET AL.: "Compression and Free Expansion of Single DNA Molecules in Nanochannels", PHYSICAL REVIEW LETTERS, vol. 95, JPN6014029866, 31 December 2005 (2005-12-31), pages 268101 - 1, ISSN: 0003181999
HAN CAO: "Gradient nanostructures for interfacing microfluidics and nanofluidics", GRADIENT NANOSTRUCTURES FOR INTERFACING MICROFLUIDICS AND NANOFLUIDICS, vol. 81, no. 16, JPN6015042789, 14 October 2002 (2002-10-14), pages 3058 - 3060, XP012032222, ISSN: 0003182000, DOI: 10.1063/1.1515115
J. T. MANNION,: "Conformational Analysis of Single DNA Molecules Undergoing Entropically Induced Motion in Nanochanne", BIOPHYSICAL JOURNAL, vol. 90, JPN6013004236, June 2006 (2006-06-01), pages 4538 - 4545, XP007910275, ISSN: 0003181996, DOI: 10.1529/biophysj.105.074732
Y.H. CHO: "Fabrication of silicon dioxide nanochannel arrays without nanolithography for manipulation of DNA mo", MICROELECTRONIC ENGINEERING, vol. 85, JPN6015001389, 13 March 2008 (2008-03-13), pages 1275 - 1277, ISSN: 0003181997
N. KAJI ET AL.: "Separation of Long DNA Molecules by Quartz Nanopillar Chips under a Direct Current Electric Field", ANAL. CHEM., vol. 76, no. 1, JPN6014029869, 1 January 2004 (2004-01-01), pages 15 - 22, XP001047450, ISSN: 0003181998, DOI: 10.1021/ac030303m
C. H. RECCIUS ET AL.: "Compression and Free Expansion of Single DNA Molecules in Nanochannels", PHYSICAL REVIEW LETTERS, vol. 95, JPN6014029866, 31 December 2005 (2005-12-31), pages 268101 - 1, ISSN: 0003181999
Attorney, Agent or Firm:
Taro Yaguchi