To obtain the subject suppressing agent useful for treating skin diseases and improving corneum troubles through the action on cells themselves by compounding a specific alcohol as an active component.
This suppressing agent is a composition containing a 15-25C terpene alcohol as an active component preferably in an amount of 0.001-20wt.%. Examples of the above terpene alcohol include a compound of formula I [a dotted line expresses a single bond or a double bond; (n)=2, 3, 4] (e.g. farnesol), a compound of formula II (e.g. geranylgeranylisopropanol), a compound of formula III [(n)=3, 4] (e.g. phytanetriol) or a compound of formula IV (e.g. isophytol). The suppressing agent can be compound with another medicinal component such as a germicidal disinfectant, an astringent agent or a skin softening agent, or an aqueous component, powder, an oil solution, a humectant, etc., which are used as a component of a cosmetic or a percutaneous medicine. The suppressing agent is preferably used as an agent for external use for skin, and ointment, milky lotion, cream, skin lotion, etc., is cited as a dosage form. When used as an agent for external use, the agent is administered 1-3 times a day at a dose of 0.1-2mg/cm2 on the entire application region.
WATANABE IKUO
HORI KIMIHIKO
