To provide a new intermediate compound effectively usable in producing cefdinir, and a method for effectively producing the cefdinir using the same.
Provided is the method for producing a cefdinir of general formula (7) characterized by comprising (a) a process of producing a compound of general formula (1) by reacting a compound of general formula (4) with an activating agent of general formula (5), (b) a process of producing a compound of general formula (2) by coupling the compound of general formula (1) produced in the process (a) with a compound of general formula (6), and then adding a secondary amine or a tertiary amine as a base to produce a compound of general formula (2), and (c) a process of reacting the compound of general formula (2) produced in the process of (b) under weakly basic conditions.
WO/2000/018412 | SOLID PHASE QUENCHING SYSTEMS |
SONG YOON SEOK
LEE SUNG JAE
KIM FUNSOBU
MOON SEONG CHEOL
DAEWOONG BIO INC
JPH1059978A | 1998-03-03 | |||
JP2000502700A | 2000-03-07 | |||
JPH1059978A | 1998-03-03 | |||
JP2006501305A | 2006-01-12 | |||
JP2000502700A | 2000-03-07 |
WO2005121154A1 | 2005-12-22 |
JPN6012006379; The Journal of Antibiotics Vol.44, No.5, p.507-516 (1991).