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Title:
カルバペネム系抗生物質の中間体及びその調製方法
Document Type and Number:
Japanese Patent JP2004505968
Kind Code:
A
Abstract:
There is disclosed an azetidinone compound of the formula (I):wherein R is hydrogen, or a hydroxy protecting group, R1 and R2 are each independently alkyl of 1-15 carbon atoms, benzyl or cyclized together with the carbon atom to which they are attached to form a 5 or 6-membered cyclic hydrocarbon or a heterocyclic radical having one or two hetero ring atoms, said hetero ring atoms being selected from the group consisting of O and S; R3 is lower alkyl or -COO(lower alkyl) R4 is phenyl, or phenyl substituted with halogen, lower alkoxy or nitro which is useful as a synthetic intermediate to the 1'beta-methylcarbapenem-type antibacterial agent.

Inventors:
Lee Chorhe
Kim bon jin
Byeon Gyu
Jeong Won Jiang
Kim Jae Ha
Kyung Hee Jung
Kwa Hyun Jung
Kim Eun Jung
Song Shin Suk
Lee Jins
Jeong Young Ho
Application Number:
JP2002518205A
Publication Date:
February 26, 2004
Filing Date:
August 06, 2001
Export Citation:
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Assignee:
Dong Wa Pharmaceutical Industrial Company Limited
KOREA GAS CORPORATION
International Classes:
C07D413/14; C07D205/08; C07D265/06; C07D265/14; C07D413/06; C07D487/04; C07D498/10; C07F7/18; C07F9/572; C07F9/6561; (IPC1-7): C07F7/18; C07D265/06; C07D498/10; C07F9/572
Domestic Patent References:
JPH0797381A1995-04-11
JPH07165760A1995-06-27
Foreign References:
US6011150A2000-01-04
Attorney, Agent or Firm:
Atsushi Nakajima
Kato Kazunori
Katsuichi Nishimoto