Title:
ジカルバメート化合物の合成法およびその作製における中間体
Document Type and Number:
Japanese Patent JP2008538565
Kind Code:
A
Abstract:
Disclosed is a method of making 2-substituted-2-halo-1,3-propanediols via reduction of corresponding malonate compounds. Also disclosed is a method of making 2-substituted-2-halo-1,3-dicarbamate compounds (such as halo derivatives of felbamate, including fluorofelbamate) via reduction of malonate compounds, followed by carbamoylation. Reduction of the malonate compounds is carried out using an electrophilic hydride reagent.
Inventors:
Motoko henry
He Wake Shan
Andersen Mark W.
Dotos Anthony K.
Lizzy
He Wake Shan
Andersen Mark W.
Dotos Anthony K.
Lizzy
Application Number:
JP2008507885A
Publication Date:
October 30, 2008
Filing Date:
April 20, 2006
Export Citation:
Assignee:
MedPoint Healthcare Incorporated
International Classes:
C07C29/147; C07C31/42; C07C269/00; C07C271/12; C07B61/00
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue