Title:
作動を停止させることができる充気交代弁を有する内燃機関
Document Type and Number:
Japanese Patent JP3612082
Kind Code:
B2
Abstract:
Novel oxyalkynes of the general formula I
in which the meta or para substituent Y denotes
R<1> denotes CH3 or NH2, R<2> denotes H or CH3 and R<3> denotes H, C1-3 -alkyl or COCH3 and Ar represents an aromatic radical from the group consisting of
with the proviso that the substituents R<4>, R<5>, and R<6> are identical or different and in each case denote H, F, Cl, Br, C1-6-alkyl, CF3 or C1-6-alkoxy and R<7> is H, F, Cl, Br, C1-3-alkyl or CF3,
as racemates or diastereomer mixtures or in optically active form and a process for their preparation are described. The oxyalkynes inhibit 5-lipoxygenase or 5- and 12-lipoxygenase and are employed as medicaments.
Inventors:
Herbert Sheepertens
Panagioteis Adamis
Joachim Naumann
Panagioteis Adamis
Joachim Naumann
Application Number:
JP7053893A
Publication Date:
January 19, 2005
Filing Date:
March 29, 1993
Export Citation:
Assignee:
VOLKSWAGEN AKTIENGESELLSCHAFT
International Classes:
A61K31/16; A61K31/17; F01L1/26; C07C259/06; C07C275/64; C07D213/42; C07D333/20; C07D521/00; F01L13/00; (IPC1-7): F01L13/00; F01L1/26
Domestic Patent References:
| JP2267322A | ||||
| JP4017705A | ||||
| JP61185605A | ||||
| JP3050313A | ||||
| JP60195913U |
Attorney, Agent or Firm:
Mitsufumi Esaki
Tsuneo Mihara
Masuo Hagiwara
Tsuneo Mihara
Masuo Hagiwara