Title:
細胞内結合タンパク質(IBP)およびその使用
Document Type and Number:
Japanese Patent JP4384260
Kind Code:
B2
Abstract:
PCT No. PCT/FR94/00714 Sec. 371 Date Dec. 28, 1995 Sec. 102(e) Date Dec. 28, 1995 PCT Filed Jun. 15, 1994 PCT Pub. No. WO94/29446 PCT Pub. Date Dec. 22, 1994The present invention relates to nucleic acid sequences encoding intracellular binding proteins. More particularly, the nucleic acid comprises a gene coding for an intracellular single chain antibody specific for a ras oncogene under the control of a promoter, the antibody is functional in mammalian cells, and inhibits the transformation of cells that express a ras oncogene.
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Inventors:
Schubaijhofer, Huabiyan
Toku, Brno
Toku, Brno
Application Number:
JP50143495A
Publication Date:
December 16, 2009
Filing Date:
June 15, 1994
Export Citation:
Assignee:
Aventis Pharma S.A.
International Classes:
A61K48/00; A61K31/70; C12N15/09; A61K39/12; C07H21/04; C07K16/00; C07K16/08; C07K16/10; C07K16/18; C07K16/32; C12N7/00; C12N15/00; C12N15/12; C12N15/13; C12N15/86; C12P21/02; C12P21/08; A61K38/00; C12R1/91
Other References:
FEBS Lett., 274 (1990) p.193-198
BIO/TECHNOLOGY, 10 (1992) p.790-794
The EMBO Journal, 9 (1990) p.101-108
Experimental Cell Research, 162 (1986) p.363-371
Science, 259 (1993 Jan.) p.525-528
J. Virol., 1982, Vol.43, No.1, pages 294-304
Nature, 1984, Vol.310, No.5973, pages 143-5
Virology, 1986, Vo.154, No.1, pages 21-30
Nucleic Acids Res., 1993, Vol.21, No.5, pages 1081-5
BIO/TECHNOLOGY, 10 (1992) p.790-794
The EMBO Journal, 9 (1990) p.101-108
Experimental Cell Research, 162 (1986) p.363-371
Science, 259 (1993 Jan.) p.525-528
J. Virol., 1982, Vol.43, No.1, pages 294-304
Nature, 1984, Vol.310, No.5973, pages 143-5
Virology, 1986, Vo.154, No.1, pages 21-30
Nucleic Acids Res., 1993, Vol.21, No.5, pages 1081-5
Attorney, Agent or Firm:
Patent business corporation Odashima patent office