Title:
中枢神経系の疾病の処置における使用のための単離されたストロマ細胞
Document Type and Number:
Japanese Patent JP4748855
Kind Code:
B2
Abstract:
Methods of treating a human patient having a disease, disorder or condition of the central nervous system are disclosed. The methods include obtaining a bone marrow sample from a human donor, isolating stromal cells from the bone marrow sample, and administering the isolated stromal cells to the central nervous system of the human patient, wherein the presence of the isolated stromal cells in the brain effects treatment of the disease, disorder or condition. Stromal cells which are isolated may be cultured in vitro, they may be genetically engineered to produce therapeutic compounds, and/or they may be predifferentiated prior to administration into the central nervous system.
Inventors:
Prokop, Derwin Jay
Stokes, David G
Aziji, S. Ausim
Finney, Donald Gee
Stokes, David G
Aziji, S. Ausim
Finney, Donald Gee
Application Number:
JP2000533087A
Publication Date:
August 17, 2011
Filing Date:
February 24, 1999
Export Citation:
Assignee:
MCP Hahnemann University
International Classes:
A61K35/28; C12N15/09; A61K38/00; A61K38/17; A61K38/22; A61K38/44; A61K39/395; A61K48/00; A61P11/00; A61P25/00; A61P25/16; A61P25/28; A61P35/00; A61P43/00; C07K14/47; C07K14/61; C07K14/745; C07K14/78; C12M3/06; C12N5/077; C12N5/0775; C12N5/079; C12N5/10; A61K35/12
Other References:
JAISWAL,N. et al,Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro,J Cell Biochem,1997年,Vol.64, No.2,p.295-312
Attorney, Agent or Firm:
Patent business corporation Odashima patent office