Title:
It is an interference RNA molecule of a new form more.
Document Type and Number:
Japanese Patent JP6069096
Kind Code:
B2
Abstract:
The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double- stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and whereby said first stretch is at least partially complementary to a target nucleic acid, and the second strand comprises a second stretch of contiguous nucleotides whereby said second stretch is at least partially identical to a target nucleic acid, and whereby the double stranded structure is blunt ended.
Inventors:
Gize, Claus
Kaufmann, Jorg
Klippel-Gize, Anke
Kaufmann, Jorg
Klippel-Gize, Anke
Application Number:
JP2013106297A
Publication Date:
January 25, 2017
Filing Date:
May 20, 2013
Export Citation:
Assignee:
Silence Therapeutics Gezelshaft Mitt Beschlenktel Haftung
International Classes:
C12N15/113; A01K67/027; A61K31/712; A61K31/713; A61K48/00; A61P3/04; A61P3/10; A61P9/00; A61P35/00; C07H21/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/11; A61K38/00
Domestic Patent References:
| JP9506248A |
Foreign References:
| WO2002044321A2 | ||||
| WO2003070895A2 | ||||
| WO2001075164A2 | ||||
| WO2002055693A2 |
Other References:
Mol. Cell,2000年,vol.6, no.5,pp.1077-1087
EMBO J.,2001年,vol.20, no.23,pp.6877-6888
Nature,2001年,vol.411, no.6836,pp.494-498
Methods,2002年 2月,vol.26, no.2,pp.199-213
EMBO J.,2001年,vol.20, no.23,pp.6877-6888
Nature,2001年,vol.411, no.6836,pp.494-498
Methods,2002年 2月,vol.26, no.2,pp.199-213
Attorney, Agent or Firm:
Patent business corporation Tsukuni